Fighting HIV: It's What's Inside That Counts (Really)

So researchers are finding another approach to battling HIV that makes use of genes we already have? Cool. Here's an excerpt from the paper that came out a few months ago:

A group of scientists led by Nitya Venkataraman and Alexander Colewhether wanted to try a new approach to fighting HIV - one that worked with the body's own immune system. They knew Old World monkeys had a built-in immunity to HIV: a protein called retrocyclin, which can prevent HIV from entering cell walls and starting an infection. So they began poring over the human genome, looking to see if humans had a latent gene that could manufacture retrocyclin too. It turned out that we did, but a "nonsense mutation" in the gene had turned it off at some point in our evolutionary history.
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The team found a way to use a compound called aminoglycosides, which itself can cause errors when RNA transcribes information from DNA to make proteins. But this time, the aminoglycoside error would work in their favor: It would cause that RNA to ignore the nonsense mutation in the junk gene, and therefore start making retrocyclin again. In preliminary tests, their scheme worked. The human cells made retrocyclin, fended off HIV, and effectively became AIDS-resistant.

Wow. Seriously, that's amazing. Unfortunately, judging by some of the comments on the article, I think a few people might interpret this the wrong way. I'm taking a look at the paper, and I want to make a few points: